502485-28-1

Basic information

• Product Name: 1,3-Benzenediol, 4-chloro-2-methyl-
• Synonyms: 1,3-Benzenediol, 4-chloro-2-methyl-;4-chloro-2-methyl-1,3-benzenediol
• CAS NO: 502485-28-1
• Molecular Formula: C₇H₇ClO₂
• Molecular Weight: 158.58
• Mol File: 502485-28-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,3-Benzenediol, 4-chloro-2-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Benzenediol, 4-chloro-2-methyl-(502485-28-1)
• EPA Substance Registry System: 1,3-Benzenediol, 4-chloro-2-methyl-(502485-28-1)

Safety Data

• Hazardous Substances Data: 502485-28-1(Hazardous Substances Data)

Usage

Physical state

White to light brown crystalline solid

Uses

a. Antiseptic
b. Disinfectant

Application areas

a. Consumer products (soaps, shampoos, lotions)
b. Industrial products (cleaning and sanitizing solutions)

Properties

a. Antibacterial
b. Antifungal

Safety concerns

Prolonged or excessive exposure can cause irritation to the skin, eyes, and respiratory system

Precaution

Use products containing 1,3-Benzenediol, 4-chloro-2-methylin accordance with safety guidelines and recommendations

Upstream product

• 128-09-6 N-chloro-succinimide 
• 608-25-3 2-methylbenzene-1,3-diol 

Relevant articles and documents

In Situ Formed IIII-Based Reagent for the Electrophilic ortho-Chlorination of Phenols and Phenol Ethers: The Use of PIFA-AlCl3 System

A new and in situ formed reagent generated by mixing PIFA {bis[(trifluoroacetoxy)iodobenzene]} and AlCl3 was introduced in the organic synthesis for the direct and highly regioselective ortho-chlorination of phenols and phenol ethers. An efficient electrophilic chlorination for these electron-rich arenes as well as the scope of the reaction are described herein. An easy, practical, and open-flask reaction allowed us to introduce a chlorine atom, which is a highly important functional group in organic synthesis. The reproducibility of our method has been demonstrated on gram-scale by carrying out the reaction in 6-bromo-2-naphthol. This halogenation reaction also proceeds in excellent conditions by first preparing the iodine(III)-based chlorinating reagent. Our new chlorinating reagent can be stored at least for two weeks at 4 °C without losing its reactivity.

Mild synthesis of asymmetric 2′-carboxyethyl-substituted fluoresceins

(Chemical Equation Presented) Asymmetric fluoresceins bearing a carboxyethyl group in the chromophoric portion of the dyes were prepared by a reaction of substituted phthalic anhydride with a carboxyethyl substituted resorcinol analogue followed by a condensation with a second resorcinol analogue. In order to avoid an accumulation of symmetric side products, the second step was performed in two substeps: acid-catalyzed formation of a triphenylmethyl intermediate followed by base-catalyzed cyclization which furnished the desired dyes.

Compounds and methods for fluorescent labeling

Compounds useful in the fluorescent labeling of biological materials are provided along with methods for their use and preparation.