502546-16-9

Basic information

• Product Name: Cyclopropanamine, N-(3-pyridinylmethylene)-, [N(E)]- (9CI)
• Synonyms: Cyclopropanamine, N-(3-pyridinylmethylene)-, [N(E)]- (9CI)
• CAS NO: 502546-16-9
• Molecular Formula: C9H10N2
• Molecular Weight: 146.1891
• Product Categories: PYRIDINE
• Mol File: 502546-16-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Cyclopropanamine, N-(3-pyridinylmethylene)-, [N(E)]- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopropanamine, N-(3-pyridinylmethylene)-, [N(E)]- (9CI)(502546-16-9)
• EPA Substance Registry System: Cyclopropanamine, N-(3-pyridinylmethylene)-, [N(E)]- (9CI)(502546-16-9)

Safety Data

• Hazardous Substances Data: 502546-16-9(Hazardous Substances Data)

Upstream product

• 500-22-1 3-pyridinecarboxaldehyde 
• 765-30-0 Cyclopropylamine 

Downstream Products

• 53844-46-5 3-(3,4-dihydro-2H-pyrrol-2-yl)-pyridine 

Relevant articles and documents

Design, Synthesis, and Biological Activity of Novel Triazole Sulfonamide Derivatives Containing a Benzylamine Moiety

The triazole sulfonamide played a very important role in the field of research of new agrochemical compounds as a novel heterocyclic compound with lack of reported resistance. For the research on the innovative triazole sulfonamide fungicide effective against cucumber downy mildew (CDM), the present article designed an array of 1,2,4-triazole-1,3-disulfonamide derivatives. The derivatives were synthesized via coupling multiple benzylamine with triazole sulfonamide groups. 1H-NMR, 13C-NMR, and LC–MS spectrometry were used to characterize these synthesized compounds. Most of these derivatives exhibited better fungicidal activities than that of the commercial cyanosole using bioassays. In particular, compounds 6g and 6h showed the best fungicidal activity against CDM (EC50?=?6.91 and 10.62?mg/L). Comparative experiments demonstrated that the fungicidal activity of 6g and 6h was better than the commercial pesticides amisulbrom and cyanosole. According to the study, the compound 6g had a giant application potential on fungicide against CDM.

Discovery of 5-phenoxy-1,3-dimethyl-1H-pyrazole-4-carboxamides as potent agonists of TGR5 via sequential combinatorial libraries

Optimization of a high-throughput screening hit led to the discovery of a new series of 5-phenoxy-1,3-dimethyl-1H-pyrazole-4-carboxamides as highly potent agonists of TGR5. This novel chemotype was rapidly developed through iterative combinatorial library synthesis. It was determined that in vitro agonist potency correlated with functional activity data from human peripheral blood monocytes.

Synthesis of C-aryl-N-cyclopropylnitrones

Synthesis of C-aryl-N-cyclopropylnitrones is described. Preparations were performed either by condensation of the appropriate aldehyde with N-cyclopropyl-hydroxylamine, or oxidation of N-substituted N-cyclopropylamines with sodium tungstate/hydrogen perox

Substituted pyridines useful as modulators of acetylcholine receptors

In accordance with the present invention, there is provided a class of pyridine compounds which are modulators of acetylcholine receptors. The compounds of the invention displace acetylcholine receptor ligands from their binding sites. Invention compounds