50299-42-8

Basic information

• Product Name: H-3,5-DIBROMO-D-TYR-OH
• Synonyms: 3,5-DIBROMO-D-TYROSINE;D-3,5-DIBROMO-D-TYROSINE;D-3,5-DIBROMOTYROSINE;H-D-TYR(3,5-BR2)-OH;H-3,5-DIBROMO-D-TYR-OH;3,5-Dibromo-D-tyrosin;(R)-2-amino-3-(3,5-dibromo-4-hydroxyphenyl)propanoic acid;H-D-Tyr(3,5-Br2)-OH 3,5-DibroMo-D-tyrosine
• CAS NO: 50299-42-8
• Molecular Formula: C₉H₉Br₂NO₃
• Molecular Weight: 338.98
• Mol File: 50299-42-8.mol

Chemical Properties

• Boiling Point: 416.6oC at 760 mmHg
• Flash Point: 205.7oC
• Appearance: /
• Density: 2.014g/cm3
• Vapor Pressure: 1.1E-07mmHg at 25°C
• Refractive Index: 1.668
• Storage Temp.: Store at RT.
• PKA: 2.16±0.30(Predicted)
• CAS DataBase Reference: H-3,5-DIBROMO-D-TYR-OH(CAS DataBase Reference)
• NIST Chemistry Reference: H-3,5-DIBROMO-D-TYR-OH(50299-42-8)
• EPA Substance Registry System: H-3,5-DIBROMO-D-TYR-OH(50299-42-8)

Safety Data

• Hazardous Substances Data: 50299-42-8(Hazardous Substances Data)

Usage

Uses

Used in Research and Pharmaceutical Development:
H-3,5-DIBROMO-D-TYR-OH is used as a research tool for studying molecular interactions and biological processes. Its unique structure allows scientists to explore its potential in modulating various biological pathways and mechanisms, contributing to a better understanding of disease processes and the development of targeted therapies.
Used in Synthesis of Novel Drug Candidates:
In the pharmaceutical industry, H-3,5-DIBROMO-D-TYR-OH is employed as a building block for the synthesis of new drug candidates. Its distinctive chemical properties make it a promising starting point for the creation of innovative therapeutic agents that can address unmet medical needs and improve patient outcomes.
Used in Drug Design and Development:
H-3,5-DIBROMO-D-TYR-OH is utilized in drug design and development as a structural component that can be modified to create new compounds with specific therapeutic properties. Its versatility in chemical reactions enables the development of drugs with tailored pharmacological profiles, enhancing their efficacy and safety in treating various diseases.

InChI:InChI=1/C9H9Br2NO3/c10-5-1-4(2-6(11)8(5)13)3-7(12)9(14)15/h1-2,7,13H,3,12H2,(H,14,15)/t7-/m1/s1

Upstream product

• 556-02-5 tyrosine 

Downstream Products

• 349535-07-5 N-[(1,1-dimethylethoxy)carbonyl]-3,5-dibromo-D-tyrosine 

Relevant articles and documents

Bromo-tyrosine alkaloidal compound as well as preparation method and application thereof

The invention belongs to the field of a medical technology, and concretely relates to a bromo-tyrosine alkaloidal compound as well as a preparation method and application thereof. The invention provides the bromo-tyrosine alkaloidal compound as shown in a general formula I and a general formula II, the preparation method thereof, and the application thereof in preparing an antitumor drug for the first time. The bromo-tyrosine alkaloidal compound has good antineoplastic activity, the preparation method is simple and feasible, the yield is better, and the bromo-tyrosine alkaloidal compound has abroad application prospect.

Bromotyrosine-derived Metabolites from the Sponge Aiolochoria crassa

A chemical investigation of secondary metabolites from the sponge Aiolochroia crassa has been performed and five bromotyrosine derivatives (1-5) were identified. Their structures have been assigned on the basis of spectroscopic analysis, of which araplysillin III (2) and hexadellin C (3) possess new structures. The absolute configurations of dibromotyrosine moieties of 2 were determined by HPLC analysis of derivatized constituent amino acids obtained from acid hydrolysis. The stereochemistry of the spirocyclohexadienylisoxazoline moiety of compounds 1-3 was deduced from spectroscopic comparison of the same moiety of aerothionin, of which the absolute configuration was previously assigned by X-ray and CD analysis. - Keywords: antibiotics; marine metabolites; spiro compounds.