- Adamantyl thioamides
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Adamantyl thioamides having the formula: EQU1 in which Ad is adamantyl or alkyl-substituted adamantyl; m is a number of 0 or 1, n is a number of 1 or 2, with the proviso that m is 1, when n is 2; and the aminothiocarbonylmethyl or the aminothiocarbonyl group is bonded to a bridgehead carbon atom of the adamantane ring, are prepared by reacting a nitrile having the formula in which Ad, m and n have the same meaning as above, with hydrogen sulfide in the presence of a catalyst. The compounds possess antiviral activity.
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