- Oxazolidin-2-one as efficient ligand for the copper-catalyzed N- Arylation of pyrrole, imidazole and indole
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Oxazolidin-2-one was found to be a facile ligand for the N-arylation of pyrrole, indole, and imidazole with aryl and heteroaryl iodides, bromides, and chlorides by applying Cul as catalyst. The easy preparation, commercial availability, lower molecular weight, and broad substrate applicability, as well as substituent compatibility of this catalysis system render oxazolidin-2-one great advantages over the Cu-catalyzed methods that have already been utilized in a number of applications.
- Ma, Hengchang,Wu, Shang,Sun, Qiangsheng,Lei, Ziqiang
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experimental part
p. 212 - 218
(2011/07/07)
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- A microwave-assisted, green procedure for the synthesis of N-aryl sulfonyl and N-aryl pyrroles
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A simplified approach to the uncatalyzed Paal-Knorr condensation using microwave irradiation in water is described.
- Wilson, Matthew A.,Filzen, Gary,Welmaker, Gregory S.
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experimental part
p. 4807 - 4809
(2009/10/26)
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- N-hydroxyimides as efficient ligands for the copper-catalyzed N-arylation of pyrrole, imidazole, and indole
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(Chemical Equation Presented) An experimentally simple, efficient, and inexpensive catalyst system was developed for the N-arylation of pyrroles, indoles, and imidazole with aryl and heteroaryl iodides, bro-mides, and chlorides by applying CuI as catalyst, N-hydroxysuccinimide (L1), N-hydroxymaleimide (L2), or N-hydroxyphthalimide (L3) as ligand, CH3ONa as base, and DMSO as solvent. A variety of functional groups are tolerated in the reaction, including those that are not compatible with Pd-catalyzed amidation methodology.
- Ma, Heng-Chang,Jiang, Xuan-Zhen
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p. 8943 - 8946
(2008/03/12)
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- SYNTHESIS OF 9H-PYRROLO-1,4-DIAZAINDOL-9-ONE
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The synthesis of 9H-pyrrolo-1,4-diazaindol-9-one was achieved either by an intramolecular electrophilic substitution of 2-chlorocarbonyl-3-N-pyrrolopyrazine 7 and 2-N-pyrrolidinocarbonyl-3-N-pyrrolopyrazine 8 or by the intramolecular nucleophilic substitution of 2-chloro-3-(2-pyrrolyl)pyrazine 12.
- Laduree, Daniel,Kashef, Hussein El,Robba, Max
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p. 299 - 301
(2007/10/02)
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