510723-68-9

Basic information

• Product Name: DIETHYL-(4-([(FURAN-2-YLMETHYL)-AMINO]-METHYL)-PHENYL)-AMINE
• Synonyms: DIETHYL-(4-([(FURAN-2-YLMETHYL)-AMINO]-METHYL)-PHENYL)-AMINE;N,N-DIETHYL-4-(((2-FURYLMETHYL)AMINO)METHYL)ANILINE
• CAS NO: 510723-68-9
• Molecular Formula: C₁₆H₂₂N₂O
• Molecular Weight: 258.36
• Mol File: 510723-68-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: DIETHYL-(4-([(FURAN-2-YLMETHYL)-AMINO]-METHYL)-PHENYL)-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: DIETHYL-(4-([(FURAN-2-YLMETHYL)-AMINO]-METHYL)-PHENYL)-AMINE(510723-68-9)
• EPA Substance Registry System: DIETHYL-(4-([(FURAN-2-YLMETHYL)-AMINO]-METHYL)-PHENYL)-AMINE(510723-68-9)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 510723-68-9(Hazardous Substances Data)

Upstream product

• 617-89-0 furan-2-ylmethanamine 
• 120-21-8 4-Diethylaminobenzaldehyde 

Downstream Products

• 1426152-06-8 N-(4-(diethylamino)benzyl)-N-(furan-2-ylmethyl)-4-isopropylbenzenesulfonamide 

Relevant articles and documents

Trisubstituted sulfonamides: A new chemotype for development of potent and selective CB2 receptor inverse agonists

An extensive exploration of the structure-activity relationship of a trisubstituted sulfonamide series led to the identification of 39, which is a potent and selective CB2 receptor inverse agonist [K i(CB2) = 5.4 nM, and Ki(CB1) = 500 nM]. The functional properties measured by cAMP assays indicated that the selected compounds were CB2 inverse agonists with high potency values (for 34, EC50 = 8.2 nM, and for 39, EC50 = 2.5 nM). Furthermore, an osteoclastogenesis bioassay indicated that trisubstituted sulfonamide compounds showed great inhibition of osteoclast formation.