cas 511-15-9, TOTAROL | Articles data

A concise route to multigram quantities of the antibacterial diterpene (+)-totarol (1) is reported. (-)-Sclareol (2) was converted to the target compound 1 using either a six- or a seven-step sequence, while only three steps were required to access (+)-totarol ( 1) starting from (+)-manool (9) or (+)-13-epi-manool (10), respectively. A novel one-pot intramolecular aldol condensation/α-alkylation protocol served as the key operation for streamlining the syntheses of 1. ARKAT-USA, Inc.

The iodination of thallium(I) salts of phenols is examined and the results are compared with those of the selective ortho-iodinating reagent thallium(I) acetate-iodine.

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Chemical Properties

Melting Point: 128-132 °C(lit.)

Boiling Point: 369.4 °C at 760 mmHg

Flash Point:166.585 °C

Density: 0.988 g/cm³

Solubility:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)

Storage Temp.:-20°C Freezer

Vapor Pressure: 5.6E-06mmHg at 25°C

Refractive Index: 1.529

PKA: 10.90±0.60(Predicted)

PSA: 20.23000

LogP: 5.54580

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511-15-9

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Chemical Properties

Melting Point: 128-132 °C(lit.)

Boiling Point: 369.4 °C at 760 mmHg

Flash Point:166.585 °C

Density: 0.988 g/cm3

Solubility:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)

Storage Temp.:-20°C Freezer

Vapor Pressure: 5.6E-06mmHg at 25°C

Refractive Index: 1.529

PKA: 10.90±0.60(Predicted)

PSA: 20.23000

LogP: 5.54580

Global suppliers and manufacturers of 511-15-9total 39 suppliers on LookChem

Density: 0.988 g/cm³