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2,3,4,6-TETRAFLUOROBENZENEBORONIC ACID, also known as (2,3,4,6-Tetrafluorophenyl)boronic acid, is a chemical compound with the molecular formula C6H3BF4O2. It is a white crystalline solid that is soluble in water and has a characteristic aromatic smell. 2,3,4,6-TETRAFLUOROBENZENEBORONIC ACID is known for its reactivity and is widely used in various chemical reactions and applications due to its unique properties.

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  • 511295-00-4 Structure
  • Basic information

    1. Product Name: 2,3,4,6-TETRAFLUOROBENZENEBORONIC ACID
    2. Synonyms: 3H-Tetrafluorobenzeneboronic acid;2,3,4,6-TETRAFLUOROBENZENEBORONIC ACID;2,3,4,6-TETRAFLUOROPHENYLBORONIC ACID
    3. CAS NO:511295-00-4
    4. Molecular Formula: C6H3BF4O2
    5. Molecular Weight: 193.89
    6. EINECS: N/A
    7. Product Categories: Aryl;Boronic Acids;Boronic Acids and Derivatives
    8. Mol File: 511295-00-4.mol
  • Chemical Properties

    1. Melting Point: 121-123°C
    2. Boiling Point: 244℃
    3. Flash Point: 101℃
    4. Appearance: /
    5. Density: 1.53
    6. Vapor Pressure: 0.0166mmHg at 25°C
    7. Refractive Index: 1.446
    8. Storage Temp.: 2-8°C
    9. Solubility: N/A
    10. BRN: 9200162
    11. CAS DataBase Reference: 2,3,4,6-TETRAFLUOROBENZENEBORONIC ACID(CAS DataBase Reference)
    12. NIST Chemistry Reference: 2,3,4,6-TETRAFLUOROBENZENEBORONIC ACID(511295-00-4)
    13. EPA Substance Registry System: 2,3,4,6-TETRAFLUOROBENZENEBORONIC ACID(511295-00-4)
  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: 36/37/38
    3. Safety Statements: 26-37
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 511295-00-4(Hazardous Substances Data)

511295-00-4 Usage

Uses

Used in Pharmaceutical Industry:
2,3,4,6-TETRAFLUOROBENZENEBORONIC ACID is used as a reactant for the Suzuki-Miyaura Coupling, a widely employed method in the synthesis of various pharmaceutical compounds. The application reason is that this boronic acid can easily form stable complexes with palladium catalysts, such as PAd3-Pd, which facilitates the coupling reaction and leads to the formation of biologically active molecules with potential therapeutic applications.
Used in Chemical Synthesis:
In the field of chemical synthesis, 2,3,4,6-TETRAFLUOROBENZENEBORONIC ACID is used as a building block for the creation of various organic compounds. The application reason is its ability to participate in a range of reactions, such as cross-coupling, substitution, and addition reactions, which allows for the synthesis of complex molecules with diverse functional groups and properties.
Used in Material Science:
2,3,4,6-TETRAFLUOROBENZENEBORONIC ACID is also used in the development of new materials, particularly in the field of polymer chemistry. The application reason is its potential to be incorporated into the backbone of polymers, which can result in materials with enhanced properties, such as improved thermal stability, chemical resistance, and mechanical strength.

Check Digit Verification of cas no

The CAS Registry Mumber 511295-00-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,1,1,2,9 and 5 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 511295-00:
(8*5)+(7*1)+(6*1)+(5*2)+(4*9)+(3*5)+(2*0)+(1*0)=114
114 % 10 = 4
So 511295-00-4 is a valid CAS Registry Number.
InChI:InChI=1/C6H3BF4O2/c8-2-1-3(9)5(10)6(11)4(2)7(12)13/h1,12-13H

511295-00-4 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
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  • Detail
  • Alfa Aesar

  • (L19825)  2,3,4,6-Tetrafluorobenzeneboronic acid, 98%   

  • 511295-00-4

  • 250mg

  • 1326.0CNY

  • Detail
  • Alfa Aesar

  • (L19825)  2,3,4,6-Tetrafluorobenzeneboronic acid, 98%   

  • 511295-00-4

  • 1g

  • 2469.0CNY

  • Detail

511295-00-4Downstream Products

511295-00-4Relevant articles and documents

Polyfluoroorganoboron-oxygen compounds. 7+. Studies of conversion of [(C6HnF5-n)B(OMe) 3]- into [(C6HnF5-n) 2B(OMe)2]- (n =

Adonin, Nicolai Yu.,Bardin, Vadim V.,Frohn, Hermann-Josef

, p. 1681 - 1692 (2008)

Conversion of salts Li[(C6HnF5-n)B(OMe) 3] (n = 0, 1) into (Li·DME)[(C6HnF 5-n)2B(OMe)2] was studied in dichloromethane-DME solution. The observed rate cons

Polyfluoroorganoboron-oxygen compounds. 1: Polyfluorinated aryl(dihydroxy)boranes and tri(aryl)boroxins

Frohn,Adonin,Bardin,Starichenko

, p. 2827 - 2833 (2008/10/08)

A general preparative procedure for polyfluorinated aryl(dihydroxy)boranes C6H5-nFnB(OH)2 (n = 3 - 5) is described. Polyfluorinated aryl(dihydroxy)boranes are easily dehydrated to the corresponding tri(aryl)boroxins (C6H5-nFnBO)3 by thermal or chemical treatment. The property of the acids C6H5-nFnB(OH)2 to condensate depends on the number and on the position of the fluorine atoms in the aryl group. Examples of both classes of boron compounds were isolated as pure individuals and characterized by multinuclear NMR spectroscopy.

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