cas 514-65-8, Bipariden | Articles data

Articles about 514-65-8Total 3 be found

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Patch and production method thereof
The present invention relates to a patch containing a substrate, a non-crosslinked adhesive layer (A) containing a drug laminated on one surface of the substrate and a crosslinked adhesive layer (B) laminated on the adhesive layer (A). According to the present invention, the percutaneous absorbability of the drug can be improved, and a patch free of problems such as adhesive residue and adhesive bleed can be provided.
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(2008/06/13)

Aryl-cycloalkyl-alkanolamines for treatment of cholinergic neurotoxins
A compound and method are disclosed for reducing neurotoxic effects (such as seizures and brain damage) caused by cholinergic agents such as soman (a nerve gas) and pilocarpine (a convulsant drug used to study the mechanisms of epilepsy). Effective treatment can be provided by administering an aryl-cycloalkylalkanolamine substance having the general formula: STR1 The compoudns procyclidine, biperiden, and trihexyphenidyl fall within this class of compounds. Although not previously recognized to be effective against soman or other cholinergic neurotoxins, all three representative compounds have been discovered to be highly effective against all cholinergic neurotoxins tested to data, even when administered after actual seizures begin.
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(2008/06/13)

Aryl-cycloalkyl-alkanolamines for treatment of neurotoxic injury
Compounds, compositions and methods of treatment are described to control brain damage associated with anoxia or ischemia which typically follows such conditions as stroke, cardiac arrest or perinatal asphyxia. The treatment includes administration of an aryl-cycloalkyl-alkanolamine compound as an antagonist to inhibit excitotoxic actions at major neuronal excitatory amino acid receptor sites.
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(2008/06/13)

Chemical Properties

Melting Point: 114 °C
Boiling Point: 462.1 °C at 760 mmHg
Flash Point:224.5 °C
Density: 1.105 g/cm³
Solubility:Chloroform (Slightly), DMSO (Slightly,Sonicated), Methanol (Slightly, Sonicated)
Storage Temp.:2-8°C
Vapor Pressure: 4.14E-09mmHg at 25°C
Refractive Index: 1.595
PKA: 14.05±0.29(Predicted)
PSA: 23.47000
LogP: 3.90030

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Wuhan Han Sheng New Material Technology Co.，Ltd
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Taizhou Crene Biotechnology co.ltd
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Zibo Hangyu Biotechnology Development Co., Ltd
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Hangzhou Lingrui Chemical Co.,Ltd.
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514-65-8

Articles about 514-65-8Total 3 be found

Chemical Properties

Melting Point: 114 °C

Boiling Point: 462.1 °C at 760 mmHg

Flash Point:224.5 °C

Density: 1.105 g/cm3

Solubility:Chloroform (Slightly), DMSO (Slightly,Sonicated), Methanol (Slightly, Sonicated)

Storage Temp.:2-8°C

Vapor Pressure: 4.14E-09mmHg at 25°C

Refractive Index: 1.595

PKA: 14.05±0.29(Predicted)

PSA: 23.47000

LogP: 3.90030

Global suppliers and manufacturers of 514-65-8total 92 suppliers on LookChem

Density: 1.105 g/cm³