51421-37-5

Usage

Uses

Used in Organic Synthesis:
(2,4-DICHLORO-BENZYL)-HYDRAZINE serves as a building block in organic synthesis, contributing to the creation of a diverse array of chemical products. Its unique structure allows it to participate in multiple types of chemical reactions, making it a valuable component in the synthesis of complex organic molecules.
Used in Chemical Reactions:
As a reagent, (2,4-DICHLORO-BENZYL)-HYDRAZINE is utilized in various chemical reactions to facilitate the transformation of other compounds. Its reactivity with different chemical groups makes it a versatile tool in the field of chemistry.
Used in Pharmaceutical Production:
(2,4-DICHLORO-BENZYL)-HYDRAZINE acts as an intermediate in the production of pharmaceuticals. Its role in the synthesis of drug compounds is crucial, as it can be used to construct the molecular frameworks of various medications.
Used in Agrochemical Production:
Similarly, in the agrochemical industry, (2,4-DICHLORO-BENZYL)-HYDRAZINE is employed as an intermediate. It plays a part in the development of agrochemicals, which are essential for enhancing crop protection and yield.
Researchers across multiple fields find (2,4-DICHLORO-BENZYL)-HYDRAZINE to be a potentially useful tool due to its structural and chemical properties, despite the need for caution in its handling and application.

Upstream product

• 94-99-5 2,4-Dichlorobenzyl chloride 

Downstream Products

• 125240-84-8 ethyl 5-amino-1-(2,4-dichlorobenzyl)-1H-pyrazole-4-carboxylate 
• 1392324-13-8 C₂₁H₂₄Cl₃N₃O₂ 
• 1392324-04-7 C₂₀H₂₂Cl₃N₃O₂ 
• 1392323-90-8 C₂₀H₂₁Cl₄N₃O₂ 
• 1000806-12-1 C₁₅H₁₁Cl₃N₄ 
• 125240-89-3 1-(2,4-Dichlorobenzyl)-5-(5-nitro-2-furfurylidene)amino-4,5-dihydropyrazolo<3,4-d>pyrimidin-4-one 
• 125240-90-6 1-(2,4-Dichloro-benzyl)-3-methyl-5-{[1-(5-nitro-furan-2-yl)-meth-(E)-ylidene]-amino}-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one 
• 125240-83-7 7-(2,4-Dichloro-benzyl)-3-formyl-7H-imidazo[1,2-c]pyrazolo[4,3-e]pyrimidine-9-carbonitrile 
• 125240-92-8 1-(2,4-Dichloro-benzyl)-3-methyl-5-pyrrol-1-yl-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one 
• 125240-91-7 1-(2,4-Dichlorobenzyl)-5-(1-pyrryl)-4,5-dihydropyrazolo<3,4-d>pyrimidin-4-one 
• 125272-69-7 5-Amino-1-(2,4-dichloro-benzyl)-3-methyl-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one 
• 125240-77-9 4-Amino-3-cyano-1-(2,4-dichlorobenzyl)pyrazolo<3,4-d>pyrimidine 
• 125240-88-2 5-Amino-1-(2,4-dichlorobenzyl)-4,5-dihydropyrazolo<3,4-d>pyrimidin-4-one 
• 125240-87-1 5-Amino-1-(2,4-dichloro-benzyl)-3-methyl-1H-pyrazole-4-carboxylic acid hydrazide 

Relevant academic research and scientific papers

SPIROPYRAZOLOPYRIDINE DERIVATIVES AND USES THEREOF FOR THE TREATMENT OF VIRAL INFECTIONS

A compound of Formula (I) is provided that has been shown to be useful for treating a disease caused by a viral infection: (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, X1, X2, X3 and X4, are as defined herein.

Synthesis and bioactivity study of 2-acylamino-substituted N'-benzylbenzohydrazide derivatives

The discovery of new safe and effective pesticides is one of the main means of providing eco-friendly agricultural agents for modern crop protection. To identify new biological molecules based of the anthranilic diamide skeleton of the novel pesticide chlorantraniliprole, which acts on the ryanodine receptor and functional groups in acyl hydrazine insect growth regulators, more than 40 new compounds of 2-acylamino-substituted N'-benzylbenzohydrazide derivatives were designed and synthesized. The structures of the new compounds were characterized using 1H nuclear magnetic resonance (NMR), high-resolution mass spectrometry (HRMS), or electron impact mass spectrometry (EI-MS), and their biological activities at a concentration of 600 mg L -1 were determined against cotton aphid (Aphis gossypii Glover), carmine spider mite (Tetranychus cinnabarinus), and diamondback moth (Plutella xylostella). The results of a preliminary assay showed that compounds 6a-I-2 and 6d-III-4 maintained the lethal activity of anthranilic diamide against P. xylostella; compounds 6c-II-4, 6d-I-7, 6d-II-1, and 6d-III-5 exhibited good lethal activity against A. gossypii; and compounds 6a-II-1, 6a-III-1, 6b-I-7, 6c-I-1, and 6c-III-5 retained promising larvicidal activities against T. cinnabarinus. In subsequent further tests against T. cinnabarinus, compounds 6a-II-1, 6a-III-1, 6c-I-1, and 6c-III-5 showed an LC50 value of -1; especially, the LC50 of compound 6a-III-1 was only 27.9 mg L-1. In conclusion, the introduction of the functional fragment-substituted acyl hydrazine improved the acaricidal activity of the anthranilic diamide skeleton, and the halogen atom at X position and the methyl group at R1 play crucial roles in the biological activities of the compounds.

ADENOSINE A2A RECEPTOR ANTAGONISTS

Compounds having the structural formula I or a pharmaceutically acceptable salt thereof, wherein: X1 and X2 are 1-3 substituents independently selected from the group consisting of H, alkyl, halo, —CF3, —OCF3, alkoxy, —OH and —CN;n is 0, 1 or 2; andR and R1 are H or alkyl; also disclosed is the use of the compounds in the treatment of CNS diseases such as Parkinson's disease, alone or in combination with other agents for treating CNS diseases, pharmaceutical compositions comprising them and kits comprising the components of the combinations.