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51596-06-6

2,5-dimethyl-1,2,4-triazolo[1,5-a]pyrimidin-7-ol, commonly known as zaleplon, is a pyrimidine derivative and a nonbenzodiazepine sedative-hypnotic medication primarily used for the treatment of insomnia. It functions by reducing brain activity, thereby promoting sleep. Zaleplon is characterized as a short-acting medication, which is typically recommended for short-term insomnia treatment. It is considered to have a lower risk of dependence and tolerance compared to other sleep aids, making it a favorable choice for certain individuals. However, it should be administered with caution and under medical supervision to prevent potential adverse effects and interactions with other medications.

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  • 51596-06-6 Structure

  • Basic information

    1. Product Name: 2,5-dimethyl-1,2,4-triazolo[1,5-a]pyrimidin-7-ol
    2. Synonyms: 2,5-Dimethyl-1,2,4-triazolo(1,5-a)pyrimidin-7-ol; 2,7-dimethyl[1,2,4]triazolo[1,5-a]pyrimidin-5(1H)-one
    3. CAS NO:51596-06-6
    4. Molecular Formula: C7H8N4O
    5. Molecular Weight: 164.1646
    6. EINECS: 257-312-7
    7. Product Categories: N/A
    8. Mol File: 51596-06-6.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 250°C at 760 mmHg
    3. Flash Point: 105°C
    4. Appearance: N/A
    5. Density: 1.51g/cm3
    6. Vapor Pressure: 0.0222mmHg at 25°C
    7. Refractive Index: 1.728
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 2,5-dimethyl-1,2,4-triazolo[1,5-a]pyrimidin-7-ol(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2,5-dimethyl-1,2,4-triazolo[1,5-a]pyrimidin-7-ol(51596-06-6)
    12. EPA Substance Registry System: 2,5-dimethyl-1,2,4-triazolo[1,5-a]pyrimidin-7-ol(51596-06-6)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 51596-06-6(Hazardous Substances Data)

51596-06-6 Usage

Uses

Used in Pharmaceutical Industry:
2,5-dimethyl-1,2,4-triazolo[1,5-a]pyrimidin-7-ol is used as a sedative-hypnotic medication for the treatment of insomnia due to its ability to slow down brain activity and promote sleep. It is particularly beneficial for short-term insomnia treatment and is preferred by some individuals due to its lower risk of dependence and tolerance compared to other sleep medications.
Used in Sleep Aid Formulations:
2,5-dimethyl-1,2,4-triazolo[1,5-a]pyrimidin-7-ol is used as an active ingredient in sleep aid formulations to provide relief from insomnia. Its short-acting nature allows for effective sleep induction without the risk of prolonged sedation, making it suitable for individuals seeking temporary relief from sleep disturbances.
Used in Research and Development:
2,5-dimethyl-1,2,4-triazolo[1,5-a]pyrimidin-7-ol is utilized in research and development for the study of sleep disorders, sleep-wake cycles, and the development of new sleep medications. Its unique properties and lower risk of dependence make it an important compound for scientific investigation and potential therapeutic applications in the field of sleep medicine.

Check Digit Verification of cas no

The CAS Registry Mumber 51596-06-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,5,9 and 6 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 51596-06:
(7*5)+(6*1)+(5*5)+(4*9)+(3*6)+(2*0)+(1*6)=126
126 % 10 = 6
So 51596-06-6 is a valid CAS Registry Number.

51596-06-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,5-dimethyl-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one

1.2 Other means of identification

Product number -
Other names 2,5-Dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-ol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:51596-06-6 SDS

51596-06-6Downstream Products

51596-06-6Relevant articles and documents

DIHYDROOROTATE DEHYDROGENASE INHIBITORS WITH SELECTIVE ANTI-MALARIAL ACTIVITY

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Page/Page column 33, (2009/07/25)

Compounds according to Formula (I), Formula (II), Formula (III), Formula (V), Formula (VI), or to Formula (VII), and pharmaceutical compositions of compounds that conform to Formula (IV) or (Formula VIII): where R1 through R33 are prescribed, selectively inhibit P. falciparum dihydroorotate dehydrogenase. Accordingly, a method for preventing and treating malaria attaches to such compounds, as well as to pharmaceutically acceptable salts, solvates, stereoisomers, tautomers, and prodrugs thereof.

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