518987-75-2

Basic information

• Product Name: 5-CYANO INDAZOLE-3-CARBOXALDEHYDE
• Synonyms: 5-CYANO INDAZOLE-3-CARBOXALDEHYDE;5-Cyano-1H-indazole-3-carboxyaldehyde;3-formyl-1H-indazole-5-carbonitrile;5-Cyano-1H-indazole-3-carbaldehyde;5-CYANO-1H-INDAZOLE-3-CARBOXALDEHYDE
• CAS NO: 518987-75-2
• Molecular Formula: C₉H₅N₃O
• Molecular Weight: 171.16
• Mol File: 518987-75-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-CYANO INDAZOLE-3-CARBOXALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-CYANO INDAZOLE-3-CARBOXALDEHYDE(518987-75-2)
• EPA Substance Registry System: 5-CYANO INDAZOLE-3-CARBOXALDEHYDE(518987-75-2)

Safety Data

• Hazardous Substances Data: 518987-75-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
5-CYANO INDAZOLE-3-CARBOXALDEHYDE is used as a key intermediate for the synthesis of potential anti-cancer and anti-inflammatory drugs. Its unique chemical structure allows for the development of new therapeutic agents that can target specific biological pathways and exhibit improved efficacy and safety profiles.
Used in Agrochemical Industry:
5-CYANO INDAZOLE-3-CARBOXALDEHYDE serves as a precursor for the synthesis of agrochemicals, including pesticides and herbicides. Its reactivity and structural properties enable the creation of novel compounds with enhanced pesticidal and herbicidal activities, contributing to more effective and environmentally friendly agricultural practices.
Used in Dye Industry:
5-CYANO INDAZOLE-3-CARBOXALDEHYDE is utilized as a building block for the synthesis of various dyes, particularly those with unique color properties and stability. Its incorporation into dye molecules can lead to the development of new dyes with improved performance characteristics, such as enhanced colorfastness and resistance to fading.
Used in Materials Science:
5-CYANO INDAZOLE-3-CARBOXALDEHYDE is being studied for its potential applications in materials science, where its unique structural properties and reactivity can be harnessed to develop new materials with specific properties. These materials could find use in various fields, such as electronics, optoelectronics, and nanotechnology.
Used in Organic Synthesis:
5-CYANO INDAZOLE-3-CARBOXALDEHYDE is employed as a valuable intermediate in organic synthesis, enabling the creation of a wide range of novel organic compounds with diverse applications. Its versatility and reactivity make it an essential component in the synthesis of complex organic molecules, contributing to advancements in various scientific and industrial fields.

Upstream product

• 15861-24-2 1H-indole-5-carbonitrile 

Downstream Products

• 677702-48-6 3-Formyl-1-(2,4,6-trimethylbenzenesulphonyl)-1H-indazole-5-carbonitrile 

Relevant articles and documents

An optimized procedure for direct access to 1: H -indazole-3-carboxaldehyde derivatives by nitrosation of indoles

Indazole derivatives are currently drawing more and more attention in medicinal chemistry as kinase inhibitors. 1H-indazole-3-carboxaldehydes are key intermediates to access to a variety of polyfunctionalized 3-substituted indazoles. We report here a general access to this motif, based on the nitrosation of indoles in a slightly acidic environment. These very mild conditions allow the conversion of both electron-rich and electron-deficient indoles into 1H-indazole-3-carboxaldehydes.

INDAZOLES AS WNT/B-CATENIN SIGNALING PATHWAY INHIBITORS AND THERAPEUTIC USES THEREOF

Described herein are methods of treating a disorder or disease in which aberrant Wnt signaling is implicated, with a variety of compounds, including Wnt inhibitor compounds. More particularly, it concerns the use of an indazole compound or analogs thereof

Indazolecarboxamide derivatives, preparation and use thereof as CDK1, CDK2 and CDK4 inhibitors

Compound corresponding to general formula (I): [image] in which, R1 represents a hydrogen or halogen atom, an NH2, NHR2, NHCOR2, NO2, CN, CH2NH2 and CH2NHR2; or alternatively R1 represents an optionally substituted phenyl or an optionally substituted heteroaromatic group; Ar represents an optionally substituted phenyl group or an optionally substituted heteroaromatic group; n represents 0, 1, 2 or 3; in the form of a base, of an addition salt with an acid, of a hydrate or of a solvate. Application in therapy.

NOVEL 2-SUBSTITUTED CYCLIC AMINES AS CALCIUM SENSING RECEPTOR MODULATORS

The present invention relates to modulators of the calcium sensing receptor having the formula I (I) wherein Ar, X, n, R, R, R, and Q are as defined herein.