A PHOTOLABILE LINKER FOR THE SOLID-PHASE SYNTHESIS OF HYDRAZIDES AND PYRANOPYRAZOLES
The photolabile hydrazine linker of the present invention is based on the o-nitro-veratryl group, which is capable of releasing hydrazide derivatives upon UV irradiation. The linker allows for a new solid-phase peptide synthesis (SPPS) strategy which is f
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Page/Page column 31; 32
(2015/03/28)
A photolabile linker for the solid-phase synthesis of peptide hydrazides and heterocycles
A photolabile hydrazine linker for the solid-phase synthesis of peptide hydrazides and hydrazine-derived heterocycles is presented. The developed protocols enable the efficient synthesis of structurally diverse peptide hydrazides derived from the standard
Qvortrup, Katrine,Komnatnyy, Vitaly V.,Nielsen, Thomas E.
supporting information
p. 4782 - 4785
(2015/04/27)
Synthesis of canine motilin, a gastric motor activity-stimulating polypeptide, and its N1-substituted analogs