- Analgesic oxazolopyridine compounds
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Compound of general formula (I): STR1 in which: X, Y, Z and T each represent, independently of one another, a nitrogen atom, a --CH= group or a group CW, in which W represents a halogen atom or a lower alkyl or alkoxy group optionally substituted with one
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- 2-Aryloxazolo- et pyridines: synthese et acylation par substitution radicalaire
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Homolytic acylation of protonated 2-aryloxazolo- and pyridines by butyraldehyde and benzaldehyde, as a source of acyl radical, gives products substituted at α and γ position in satisfactory yields.The factors affecting mono- and poly-substit
- Flouzat, C.,Guillaumet, G.
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p. 899 - 906
(2007/10/02)
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- Anti-inflammatory oxazole[4,5-b]pyridines
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The various isomers of oxazolo- and thiazolopyridines having utility as antiinflammatory, antipyretic and analgesic agents are prepared by condensation of an appropriate amino-hydroxypyridine or amino-mercaptopyridine with a carboxylic acid, halide or anhydride.
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