- DESTABILIZED CARBOCATIONS. NUCLEAR MATNETIC RESONANCE DETECTION AND REACTIVITIES OF ARYL α-THIOFORMAMIDYL CATIONS
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A series of α-aryl and diarylthioformamidyl cations were observed by low-temperature nuclear magnetic resonance spectroscopy.These ions undergo efficient cyclization and deprotonation to give benzothiophenes.
- Ablenas, F. J.,George, B. E.,Maleki, M.,Jain, R.,Hopkinson, A. C.,Lee-Ruff, E.
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p. 1800 - 1803
(2007/10/02)
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- 10. Nucleophile Aminoalkylierung mit Thiopivalamiden
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Of the twelwe thioamides 7a-e and 8a-g, only N,N-dimethylthiopivalamide (7a) could be metallated at the CH-group in α-position to the N-atom.The reagent 9 thus obtained (Table 1) reacts in high yields with primary haloalkanes, with aldehydes, and with non-enolizable ketones (Table 2).As shown in Scheme 1, the products can be hydrolyzed to pivalamides, cleaved to secondary amines, or reduced to neopentylamines (see 18/19, 15/equation (4) and (5), and 16/20, respectively).
- Lubosch, Winfried,Seebach, Dieter
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p. 102 - 116
(2007/10/02)
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