530098-58-9

Basic information

• Product Name: 1-Piperazineaceticacid,4-ethyl-,methylester(9CI)
• Synonyms: 1-Piperazineaceticacid,4-ethyl-,methylester(9CI);METHYL (4-ETHYLPIPERAZIN-1-YL)ACETATE
• CAS NO: 530098-58-9
• Molecular Formula: C₉H₁₈N₂O₂
• Molecular Weight: 186.25
• Product Categories: PIPERIDINE
• Mol File: 530098-58-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Piperazineaceticacid,4-ethyl-,methylester(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperazineaceticacid,4-ethyl-,methylester(9CI)(530098-58-9)
• EPA Substance Registry System: 1-Piperazineaceticacid,4-ethyl-,methylester(9CI)(530098-58-9)

Safety Data

• Hazardous Substances Data: 530098-58-9(Hazardous Substances Data)

Upstream product

• 5308-25-8 4-ethylpiperazine 
• 96-34-4 methyl chloroacetate 

Downstream Products

• 382-27-4 Perfluoro-N,N-dimethylaminoacetyl fluoride 
• 359-70-6 perfluorotriethylamine 
• 530098-59-0 perfluoro(4-ethylpiperazin-1-ylacetyl fluoride) 

Relevant articles and documents

NK1 and NK3 antagonists

The invention is to a compound exhibiting neurokinin inhibitory properties, a pharmaceutical composition comprising same and a method of treatment for neurokinin-mediated conditions.

Simons electrochemical fluorination of substituted homopiperazines(hexahydro-1,4-diazepines) and piperazines

Simons electrochemical fluorination (ECF) of 1,4-dimethyl-1,4-homopiperazine, methyl 4-ethylhomopiperazin-1-ylacetate and 1,4-bis(methoxycarbonylmethyl)-1,4-homopiperazine was studied. For comparison, ECF of three piperazines with a N-(methoxycarbonylmethyl) group(s) was also studied. ECF of 1,4-dimethyl-1,4-homopiperazine gave a low yield of corresponding perfluoro(1,4-dimethyl-1,4-homopiperazine) together with perfluoro(2,6-diaza-2,6-dimethylheptane) as the major product. Corresponding perfluoro(homopiperazines) with mono- and/or di-(fluorocarbonyldifluoromethyl) groups [-CF2C(O)F] at the 1- and/or 4-position were formed in low yields from methyl 4-ethylhomopiperazin-1-ylacetate and 1,4-bis(methoxycarbonylmethyl)-1,4-homopiperazine, respectively. These new seven-membered perfluoro(1,4-dialkyl-1,4-homopiperazines) were accompanied by the formation of mono- and/or di-basic linear perfluoroacid fluorides resulting from the C-C bond scission at the 2- and 3-positions of the ring. From mono- and/or di-N-(methoxycarbonylmethyl)-substituted piperazines, corresponding perfluoropeperazines having the acid fluoride group(s) were formed in low yields.