- Synthesis of perhydrooxazinones from 2-aza-3-trimethylsilyloxy-1,3- butadiene. A general route to 3,3-disubstituted-β-hydroxy acids
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1-Phenyl-2-aza-3-trimethylsilyloxy-1,3-butadiene reacts with aliphatic, aromatic and cyclic ketones to give in good to excellent yields 6,6- disubstituted-1,3-perhydro-oxazin-4-ones which, in turn, have been readily converted into β-hydroxy carboxylic acids.
- Bandini, Elisa,Martelli, Giorgio,Spunta, Giuseppe,Bongini, Alessandro,Panunzio, Mauro
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p. 1735 - 1738
(2007/10/03)
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