536747-87-2

Basic information

• Product Name: (R)-1-Boc-4,4-difluoropyrrolidine-2-carboxylic acid
• Synonyms: (R)-1-Boc-4,4-difluoropyrrolidine-2-carboxylic acid;(2R)-1-[(tert-butoxy)carbonyl]-4,4-difluoropyrrolidine-2-carboxylic acid;(R)-1-(tert-Butoxycarbonyl)-4,4-difluoropyrrolidine-2-carboxylic acid;4,4-Difluoro-1-Boc-D-proline
• CAS NO: 536747-87-2
• Molecular Formula: C₁₀H₁₅F₂NO₄
• Molecular Weight: 251.2272064
• Mol File: 536747-87-2.mol

Chemical Properties

• Boiling Point: 340.4±42.0 °C(Predicted)
• Appearance: /
• Density: 1.31±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 3.06±0.40(Predicted)
• CAS DataBase Reference: (R)-1-Boc-4,4-difluoropyrrolidine-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-Boc-4,4-difluoropyrrolidine-2-carboxylic acid(536747-87-2)
• EPA Substance Registry System: (R)-1-Boc-4,4-difluoropyrrolidine-2-carboxylic acid(536747-87-2)

Safety Data

• Hazardous Substances Data: 536747-87-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(R)-1-Boc-4,4-difluoropyrrolidine-2-carboxylic acid is used as a building block for the preparation of various pharmaceutical compounds. Its chiral (R) configuration allows for the synthesis of enantiopure compounds with specific biological activity, which is crucial for the development of new drugs with targeted therapeutic effects.
Used in Agrochemical Industry:
In the agrochemical industry, (R)-1-Boc-4,4-difluoropyrrolidine-2-carboxylic acid serves as a key intermediate for the synthesis of crop protection products. Its unique structure and functional groups contribute to the development of innovative agrochemicals with enhanced efficacy and selectivity.
Used in Organic Synthesis:
(R)-1-Boc-4,4-difluoropyrrolidine-2-carboxylic acid is utilized as a versatile building block in organic synthesis. Its Boc protecting group and fluorine atoms at the 4th position enable the synthesis of a wide range of organic compounds with diverse applications in various industries.

Upstream product

• 135042-12-5 (4R)-1-(tert-butoxycarbonyl)-4-hydroxy-D-proline 
• 647857-74-7 methyl (R)-1-tert-butoxycarbonyl-4,4-difluoropyrrolidine-2-carboxylate 
• 256487-77-1 (R)-4-oxo-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester 
• 2584-71-6 cis-hydroxy-D-proline 
• 114676-69-6 (2R,4R)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate 
• 114676-59-4 (2R,4R)-4-hydroxy-2-methoxycarbonylpyrrolidine hydrochloride 

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