Synthesis of monomethylated dioscin derivatives and their antitumor activities
All possible eight monomethylated dioscin derivatives (1-8) were synthesized. Their inhibitory activities against P388 and A-549 cells were determined, and the results indicate that six of the eight hydroxyls of dioscin are the 'key polar groupings' for tumor inhibitory activities.
Li, Ming,Han, Xiuwen,Yu, Biao
p. 117 - 121
(2007/10/03)
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