53823-02-2

Basic information

• Product Name: Onitin
• Synonyms: Onitin;2,3-Dihydro-4-hydroxy-6-(2-hydroxyethyl)-2,2,5,7-tetramethyl-1H-inden-1-one;1H-Inden-1-one,2,3-dihydro-4-hydroxy-6-(2-hydroxyethyl)-2,2,5,7-tetraMethyl-
• CAS NO: 53823-02-2
• Molecular Formula: C15H20O3
• Molecular Weight: 248.32
• Mol File: 53823-02-2.mol

Chemical Properties

• Melting Point: 212 °C
• Boiling Point: 445.3°C at 760 mmHg
• Flash Point: 237.3°C
• Appearance: /
• Density: 1.156g/cm³
• Vapor Pressure: 1.03E-08mmHg at 25°C
• Refractive Index: 1.57
• PKA: 9.76±0.40(Predicted)
• CAS DataBase Reference: Onitin(CAS DataBase Reference)
• NIST Chemistry Reference: Onitin(53823-02-2)
• EPA Substance Registry System: Onitin(53823-02-2)

Safety Data

• Hazardous Substances Data: 53823-02-2(Hazardous Substances Data)

Usage

Uses

Since there is no data available about a chemical named "Onitin," it is not possible to list its uses. If "Onitin" is a misspelling or a proprietary name, please provide the correct name or additional details to discuss its potential applications in various industries. If it is a brand name or a proprietary blend, the uses would depend on the specific components and their properties, which would need to be identified and analyzed.

InChI:InChI=1/C15H20O3/c1-8-10(5-6-16)9(2)13(17)11-7-15(3,4)14(18)12(8)11/h16-17H,5-7H2,1-4H3

Upstream product

• 118304-40-8 4-Methoxy-6-β-methoxyethyl-2,2,5,7-tetramethylindan-1-one 

Relevant articles and documents

Total Synthesis of Onitin

The total synthesis of the phenolic sesquiterpene onitin using dimethylated indanone as the key intermediate is reported. Key to the success of this synthesis route is the Suzuki-Miyaura cross-coupling reaction of aryl bromide to introduce the vinyl side chain followed by formyl selective Wacker oxidation to generate the aldehyde. The target aldehyde was also obtained in high overall yield via an acid-catalyzed pinacol-pinacolone-type rearrangement of the epoxide. The epoxide was generated from oxidation of a styrene derivative by oxone. Demethylation of the aldehyde followed by chemoselective reduction furnished onitin.

FLAVONONE AND OTHER CONSTITUENTS FROM ONYCHIUM SILICULOSUM

Key Word Index - Onychium siliculosum; Pteridaceae; pterosins; flavonones; structure elucidation. Two new compounds, onitinoside and onysilin along with the known compounds, pinostrobin, onitin, onitisin, campesterol, sitosterol and n-alkanes (C25-C33) were isolated from Onychium siliculosum.Onitinoside and onysilin were identified by spectral and chemical methods as 4-O-glucosyl-6-(2'-hydroxyethyl)-2,2,5,7-tetramethylindan-1-one and 5-hydroxy-6,7-dimethoxyflavonone, respectively.

Synthesis of (+/-)-Pterosin-M and Onitin

2,4-Dimethyl-3-carbomethoxymethylanisole (3) on LAH reduction gives the alcohol (4) which is converted into the methyl ether (5).Formylation of 5 to 6, followed by Horner reaction on 6 with the appropriate phosphonate yields the unsaturated ester (7) whic