54149-49-4 Usage
Uses
Used in Bioconjugation:
Aminooxy-PEG2-methane is used as a bioconjugation agent for the formation of stable oxime and hydroxylamine linkages. Its application reason is the ability to react with aldehydes and, in the presence of a reductant, form hydroxylamine bonds, which are crucial for the attachment of biological molecules to various surfaces or other biomolecules.
Used in Drug Delivery Systems:
In the pharmaceutical industry, Aminooxy-PEG2-methane is used as a component in drug delivery systems for enhancing the solubility, stability, and bioavailability of therapeutic agents. Its application reason is the PEGylation effect, which can improve the pharmacokinetic properties of drugs and reduce their immunogenicity.
Used in Diagnostics:
Aminooxy-PEG2-methane is used as a diagnostic tool for the detection and imaging of various biological targets. Its application reason is the ability to form stable covalent bonds with target molecules, allowing for the development of highly specific and sensitive diagnostic assays.
Used in Material Science:
In the field of material science, Aminooxy-PEG2-methane is used as a component in the development of biocompatible materials and coatings. Its application reason is the ability to form stable linkages with a variety of surfaces, enabling the creation of materials with tailored properties for specific applications, such as tissue engineering and implantable devices.
Used in Research and Development:
Aminooxy-PEG2-methane is used as a research tool for the development of novel bioconjugation strategies and the study of molecular interactions. Its application reason is the versatility of the aminooxy group, which allows for the exploration of new methods and techniques in the field of biochemistry and molecular biology.
Check Digit Verification of cas no
The CAS Registry Mumber 54149-49-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,1,4 and 9 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 54149-49:
(7*5)+(6*4)+(5*1)+(4*4)+(3*9)+(2*4)+(1*9)=124
124 % 10 = 4
So 54149-49-4 is a valid CAS Registry Number.
54149-49-4Relevant articles and documents
Tandem Functionalization in a Highly Branched Polymer with Layered Structure
Cao, Xiaosong,Shi, Yi,Gan, Weiping,Gao, Haifeng
supporting information, p. 5974 - 5981 (2018/03/26)
A hyperbranched polymer with multilayer structure was developed to demonstrate the possibility of highly efficient tandem functionalization reactions at different domains within one nanostructured platform. The polymer scaffold was constructed by chain-growth copper-catalyzed azide–alkyne cycloaddition polymerization of three functional monomers with sequential monomer addition in one pot. Subsequent reactions with different monomer units resulted in efficient functionalization of each segment with construction of a highly sophisticated polymer structure by a robust procedure. As a proof of concept, the ability of this polymer structure to quantitatively load six species of guest molecules through three different types of conjugation reactions was demonstrated.
Oxygenated esters of 4-lodo phenylamino benzhydroxamic acids
-
, (2008/06/13)
The present invention relates to oxygenated esters of 4-iodophenylamino benzhydroxamic acid derivatives, pharmaceutical compositions and methods of use thereof. The present invention also relates to crystaline forms of oxygenated esters of 4-iodophenylamino benzhydroxamic acid derivatives, pharmaceutical compositions and methods of use thereof.
