- Pd(II)-Catalyzed Enantioselective Desymmetrization of Polycyclic Cyclohexenediones: Conjugate Addition versus Oxidative Heck
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Pd(II)-catalyzed desymmetrization of polycyclic cyclohexenediones has been achieved with high enantio- and diastereoselectivities. Up to five contiguous stereocenters are desymmetrized, while simultaneously, an additional stereocenter is created by the enantioselective conjugate addition. Surprisingly, the conjugate addition products dominate even under typical oxidative Heck conditions, and these observations may provide some insight into the competition between the two related reactions.
- Lamb, Claire J. C.,Vilela, Filipe,Lee, Ai-Lan
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supporting information
p. 8689 - 8694
(2019/11/03)
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- Structure of 2(5)-Alkyl-4-hydroxy-3,4-diphenylcyclopent-2-en-1-ones, cyclocondensation products of benzil with aliphatic ketones
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The reaction of benzil with methyl alkyl ketones gave three isomeric cyclopentenone derivatives, 2-substituted and cis- and trans-5-substituted 4-hydroxy-3,4-diphenylcyclopent-2-en-1-ones. cis- and trans-2,5-Disubstituted 4-hydroxy-3,4-diphenylcyclopent-2-en-1-ones were formed in analogous reaction of benzil with dialkyl ketones. The structure of the products was confirmed by 1H NMR spectroscopy and molecular- mechanics calculations. Pleiades Publishing, Ltd., 2010.
- Mikhura,Formanovskii,Shashkov
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experimental part
p. 1116 - 1120
(2011/04/19)
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- Synthesis, reactivity, and electronic properties of 6,6-dicyanofulvenes
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A series of 6,6-dicyanofulvene derivatives are synthesized starting from masked, dimeric, or monomeric cyclopentadienones. The reactivities of 6,6-dicyanofulvenes relative to their parent cyclopentadienones are discussed. 6,6-Dicyanofulvenes are capable o
- Andrew, Trisha L.,Cox, Jason R.,Swager, Timothy M.
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supporting information; experimental part
p. 5302 - 5305
(2011/02/21)
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