Lewis Acid-Catalyzed Deprotection of p-Methoxybenzyl Ether
The p-methoxybenzyl protecting group was readily removed from alcohols and phenols using catalytic amounts of AlCl3 or SnCl2 · 2H2O in the presence of EtSH at room temperature. Under these mild conditions other protecting groups such as methyl and benzyl ethers, p-nitrobenzoyl esters, TBDPS ethers and isopropylidene acetal were unchanged.
Bouzide, Abderrahim,Sauvé, Gilles
p. 1153 - 1154
(2007/10/03)
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