544655-29-0

Basic information

• Product Name: N-(3,4-dichlorobenzyl)[1,1'-biphenyl]-4-carboxamide
• Synonyms: N-(3,4-dichlorobenzyl)[1,1'-biphenyl]-4-carboxamide
• CAS NO: 544655-29-0
• Molecular Formula: C20H15Cl2NO
• Molecular Weight: 356.2452
• Mol File: 544655-29-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(3,4-dichlorobenzyl)[1,1'-biphenyl]-4-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3,4-dichlorobenzyl)[1,1'-biphenyl]-4-carboxamide(544655-29-0)
• EPA Substance Registry System: N-(3,4-dichlorobenzyl)[1,1'-biphenyl]-4-carboxamide(544655-29-0)

Safety Data

• Hazardous Substances Data: 544655-29-0(Hazardous Substances Data)

Relevant articles and documents

Alpha-helical mimetics

Benzoyl urea derivatives that are alpha helical peptides mimetics that mimic BH3-only proteins, compositions containing them, their conjugation to cell-targeting-moieties, and their use in the regulation of cell death are disclosed. The benzoyl urea derivatives are capable of binding to and neutralizing pro-survival Bcl-2 proteins. Use of benzoyl urea derivatives in the treatment and/or prophylaxis of diseases or conditions associated with deregulation of cell death are also described.

ALPHA-HELICAL MIMETICS

Benzoyl urea derivatives that are alpha helical peptide mimetics that mimic BH3-only proteins, compositions containing them, their conjugation to cell-targeting moieties, and their use in the regulation of cell death are disclosed. The benzoyl urea derivatives are capable of binding to and neutralising pro-survival Bcl-2 proteins. Use of the benzoyl urea derivatives in the treatment and/or prophylaxis of diseases or conditions associated with deregulation of cell death are also disclosed.