546112-30-5

Basic information

• Product Name: Hydrazinecarbothioamide, 2-[1-(3,5-dihydroxyphenyl)ethylidene]- (9CI)
• Synonyms: Hydrazinecarbothioamide, 2-[1-(3,5-dihydroxyphenyl)ethylidene]- (9CI)
• CAS NO: 546112-30-5
• Molecular Formula: C9H11N3O2S
• Molecular Weight: 225.27
• Product Categories: ALCOHOL
• Mol File: 546112-30-5.mol

Chemical Properties

• Boiling Point: 437.1±38.0 °C(Predicted)
• Appearance: /
• Density: 1.42±0.1 g/cm3(Predicted)
• PKA: 8.41±0.10(Predicted)
• CAS DataBase Reference: Hydrazinecarbothioamide, 2-[1-(3,5-dihydroxyphenyl)ethylidene]- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Hydrazinecarbothioamide, 2-[1-(3,5-dihydroxyphenyl)ethylidene]- (9CI)(546112-30-5)
• EPA Substance Registry System: Hydrazinecarbothioamide, 2-[1-(3,5-dihydroxyphenyl)ethylidene]- (9CI)(546112-30-5)

Safety Data

• Hazardous Substances Data: 546112-30-5(Hazardous Substances Data)

Relevant articles and documents

M-STAGE KINESIN INHIBITOR

A mitotic kinesin Eg5 inhibitor which comprises a thiadiazoline derivative represented by the general formula (I) or a pharmacologically acceptable salt thereof as an active ingredient: [wherein R1 represents a hydrogen atom and the like, R2 represents a hydrogen atom, -C(=W)R6 (wherein W represents an oxygen atom or a sulfur atom, and R6 represents substituted or unsubstituted lower alkyl and the like) and the like, R3 represents -C(=Z)R19 (wherein Z represents an oxygen atom or a sulfur atom, and R19 represents substituted or unsubstituted lower alkyl and the like) and the like, R4 represents substituted or unsubstituted lower alkyl and the like, and R5 represents substituted or unsubstituted aryl and the like] and the like are provided.

THIADIAZOLINE DERIVATIVE

(wherein R1 and R4 are the same or different and each represents a hydrogen atom, substituted or unsubstituted lower alkyl, substituted or unsubstituted lower alkynyl, substituted or unsubstituted lower alkenyl, or the like; R5 represents a substituted or unsubstituted heterocyclic group, substituted or unsubstituted aryl, or the like; R2 represents -C(-W)R6 or the like; R3 represents a hydrogen atom, -C(=WA)R6A, or the like) Antitumor agents which comprises a thiadiazoline derivative represented by the aforementioned general formula (I) or a pharmacologically acceptable salt thereof as an active ingredient are provided.