- SELECTIVE REDUCTION of 2-CARBAMOYL-1-PHENYL-1,4-DIHYDROISOQUINOLIN-3(2H)-ONES
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Treatment of 2-carbamoyl-1-phenyl-1,4-dihydroisoquinolin-3(2H)-ones (1) with lithium aluminium hydride or diborane resulted always in the reduction of the ring carbonyl group and, depending on the nature of the reducing agent and the structure of the starting compound 1,2,3,4-tetrahydro- (2), 1,2-dihydroisoquinoline derivatives (3) or 1,2,3,4-tetrahydroisoquinolin-3-ols (5) were obtained.
- Zara-Kaczian, Erzsebet,Deak, Gyula,Toth, Gabor
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p. 2533 - 2555
(2007/10/02)
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