- Synthetic method of 2-methoxyl-3-amino-5-pyridineboronic acid pinacol ester and intermediate thereof
-
The invention relates to a synthetic method of 2-methoxyl-3-amino-5-pyridineboronic acid pinacol ester and an intermediate thereof. Specifically, the synthetic method is characterized in that the 2-methoxyl-3-amino-5-pyridineboronic acid pinacol ester is obtained by the steps of taking 2-methoxylnicotinic acid as a starting raw material, halogenating, degrading, deprotecting and coupling. The method disclosed by the invention has the advantages of being short in synthesis route, simple, convenient, low in economic cost and highly suitable for industrial production.
- -
-
Paragraph 0101-0103; 0113-0115; 0125-0127
(2019/04/04)
-
- TETRACYCLIC HETEROCYCLE COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES
-
The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
- -
-
Paragraph 0572
(2014/08/07)
-
- TETRACYCLIC HETEROCYCLE COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES
-
The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
- -
-
Page/Page column 144
(2013/03/26)
-
