Solution-phase and solid-phase syntheses of enzyme inhibitor RK-682 and antibiotic agglomerins
The enzyme inhibitor RK-682 (5A)-(+)-1 was prepared in solution and on a solid support from (2R)-glycerates in five steps and ca. 40% overall yield. Key steps were a ring-closing tandem addition-Wittig alkenation reaction of the respective protected or im
Schobert, Rainer,Jagusch, Garsten
p. 6129 - 6132
(2007/10/03)
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