- Synthesis of polyhydroxylated azetidine iminosugars and 3-hydroxy-N-methylazetidine-2-carboxylic acid from d-glucose
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The azetidine iminosugars, (2S,3R)-2-((R)-1,2-dihydroxyethyl)azetidin-3-ol 3, (2R,3R)-2-(hydroxymethyl)azetidin-3-ol 4, and (2S,3R)-3-hydroxy-N-methylazetidine-2-carboxylic acid 5 were synthesized from d-glucose derived 3-N-benzyloxycarbonyl-3-deoxy-1,2-O
- Lawande, Pravin P.,Sontakke, Vyankat A.,Nair, Roopa J.,Khan, Ayesha,Sabharwal, Sushma G.,Shinde, Vaishali S.
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- Synthesis, conformational study, glycosidase inhibitory activity and molecular docking studies of dihydroxylated 4- and 5-amino-iminosugars
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An efficient methodology for the synthesis of new amino iminosugars 6a, 7a and 8, starting from d-glucose, is reported. The conformational study using 1H NMR data showed that the amino iminosugar 6a exists in the 2C5 while
- Kasture, Vijay M.,Kalamkar, Navnath B.,Nair, Roopa J.,Joshi, Rakesh S.,Sabharwal, Sushma G.,Dhavale, Dilip D.
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