552309-42-9 Usage
Uses
Used in Pharmaceutical Industry:
TMEM16AInhibitorsRevealTMEM16A(T16Ainh-A01) is used as a therapeutic agent for the treatment of various medical conditions, including hypertension, pain, diarrhea, and mucus overproduction. Its selective inhibition of TMEM16A channels makes it a promising candidate for developing targeted treatments for these ailments.
Used in Research Applications:
T16Ainh-A01 has been utilized as an inhibitor of transmembrane protein 16A (TMEM16A) in research settings. This allows scientists to study the role of TMEM16A in various biological processes and diseases, contributing to a better understanding of its function and potential therapeutic applications.
Used in Drug Development:
As a selective inhibitor of TMEM16A, T16Ainh-A01 can be employed in the development of new drugs targeting this channel. Its ability to block calcium-activated chloride channels in vascular smooth muscle cells and relax blood vessels makes it a valuable tool in the creation of medications for cardiovascular diseases and other related conditions.
Biochem/physiol Actions
T16Ainh-A01 is a selective TMEM16A calcium-activated chloride channel inhibitor that strongly inhibits chloride current in salivary gland cells. T16Ainh-A01 poorly inhibited total CaCC current in intestinal and airway epithelial cells, but blocked mainly an initial, agonist-stimulated transient chloride current. T16Ainh-A01 does not alter cytoplasmic calcium and has little effect on CFTR Cl- conductance.
Check Digit Verification of cas no
The CAS Registry Mumber 552309-42-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,5,2,3,0 and 9 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 552309-42:
(8*5)+(7*5)+(6*2)+(5*3)+(4*0)+(3*9)+(2*4)+(1*2)=139
139 % 10 = 9
So 552309-42-9 is a valid CAS Registry Number.
