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5526-13-6

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Synthesis of Indole-Dihydroisoquinoline Sulfonyl Ureas via Three-Component Reactions
Isoquinolines activated with sulfamoyl chlorides were reacted with indoles in a 3-component reaction to generate a library of dihydroisoquinoline derivatives. Using a differential protecting group strategy, products could be further derivatised. Synthesis of isoquinoline starting materials using several different methods is also described.
Pearson, Stuart E.,Fillery, Shaun M.,Goldberg, Kristin,Demeritt, Julie E.,Eden, Jonathan,Finlayson, Jonathan,Patel, Anil
p. 4963 - 4981
(2018/12/13)

Benzylic Hydroperoxide Rearrangement: Observations on a Viable and Convenient Alternative to the Baeyer-Villiger Rearrangement
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Boger, Dale L.,Coleman, Robert S.
p. 5436 - 5439
(2007/10/02)

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Chemical Properties

Storage Temp.:Sealed in dry,Room Temperature
PSA: 42.09000
LogP: 2.09320

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