Boric acid as cost-effective and recyclable catalyst for trimethylsilyl protection and deprotection of alcohols and phenols
Boric acid has been used as a green, selective and recyclable catalyst for trimethysilylation of alcohols and phenols using hexamethyldisilazane in acetonitrile. Deprotection of trimethylsilyl ethers to their parent alcohols and phenols was also achieved using this catalyst in water at room temperature. The salient features of this methodology are cheap processing, mild acidity conditions, excellent yields of products and easy availability of the catalyst.
Rostami, Amin,Akradi, Jamal,Ahmad-Jangi, Firoz
experimental part
p. 1587 - 1592
(2010/11/04)
Green and efficient procedure for the trimethylsilylation of hydroxy groups and their regeneration using sulfamic acid as recyclable catalyst
Structurally diverse alcohols and phenols were efficiently transformed into their corresponding trimethylsilyl ethers with hexamethyldisilazane (HMDS) in the presence of catalytic amounts of sulfamic acid (SA) at room temperature under both acetonitrile and solvent-free conditions. Deprotection of these trimethylsilyl ethers to their parent alcohols and phenols was also achieved using this catalyst in water at room temperature. Copyright Taylor & Francis Group, LLC.
Rostami, Amin,Ahmad-Jangi, Firoz,Zarebin, Mohammad Rezgar,Akradi, Jamal
experimental part
p. 1500 - 1507
(2010/07/15)
Novel and highly effective method for the trimethylsilylation of alcohols and phenols with hexamethyldisilazane (HMDS), catalyzed by I2 generated in situ using Fe(NO3)3 · 9 H 2O/NaI under heterogeneous and neutral conditions
Structurally diverse alcohols and phenols were trimethylsilylated in a clean and efficient reaction with hexamethyldisilazane (HMDS) based on the use of I2 generated in situ from Fe(NO3)3 · 9 H2O/NaI. The reaction occurs very rapid in good-to-high yield in CH2Cl2 at room temperature, and the use of toxic and corrosive molecular I2 is avoided.
Khazaei, Ardeshir,Rahmati, Sadegh,Rostami, Amin
experimental part
p. 1434 - 1438
(2009/10/16)
P-toluenesulfonyl chloride (p-TsCl)-catalyzed trimethylsilylation of hydroxyl groups using hexamethyldisilazane and their regeneration under mild conditions: The first example for catalytic application of p-toluenesulfonyl chloride
The first catalytic application of p-toluenesulfonyl chloride (p-TsCl) for the efficient and selective trimethylsilylation of various types of hydroxyl groups with hexamethyldisilazane (HMDS) in dichloromethane and desilylation of these compounds in water is reported. The reactions were carried out at room temperature and were found to proceed in good to excellent yields.
Mild and highly efficient method for the silylation of alcohols using hexamethyldisilazane catalyzed by iodine under nearly neutral reaction conditions
-
Karimi,Golshani
p. 7228 - 7230
(2007/10/03)
More Articles about upstream products of 55724-30-6