TRANSDERMAL DEVICE CONTAINING POLYVINYLPYRROLIDONE AS SOLUBILITY ENHANCER
A blend of at least three polymers, including a soluble polyvinylpyrrolidone, in combination with a drug provides a pressure-sensitive adhesive composition for a transdermal drug delivery system in which the drug is delivered from the pressure-sensitive adhesive composition and through dermis when the pressure-sensitive adhesive composition is in contact with human skin. Soluble polyvinylpyrrolidone increases the solubility of drug without negatively affecting the adhesivity of the composition or the rate of drug delivery from the pressure-sensitive adhesive composition
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(2008/06/13)
N4 -acylarabinonucleosides
An N4 -acyl-1-β-D-arabinofuranosylcytosine having the following formula SPC1 Wherein R is an aliphatic acyl group having 3 to 35 carbon atoms. The compounds of this invention are useful as a cancer chemotherapeutic agent for controlling tumors, e.g., in mice, an insecticide, and a fungicidal surface active agent.
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(2008/06/13)
Chemical Properties
Melting Point: 141-142°C
Boiling Point: °Cat760mmHg
Flash Point:°C
Density: 1.16g/cm3
Solubility:DMSO (Slightly, Heated), Methanol (Slightly, Heated), THF (Slightly, Heated, Son