558466-12-9 Usage
Uses
Used in Organic Synthesis:
3-Pyridinethiol,6-chloro-(9CI) is used as a key intermediate in organic synthesis for the creation of a variety of complex organic molecules. Its unique structure, which includes both a thiol and a chlorine atom, allows for versatile chemical reactions and the formation of diverse molecular architectures.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 3-Pyridinethiol,6-chloro-(9CI) serves as a valuable building block for the development of pharmaceutical compounds. Its incorporation into drug molecules can potentially enhance their therapeutic properties, such as improving binding affinity to target proteins or modulating pharmacokinetic profiles.
Used in Pharmaceutical Development:
3-Pyridinethiol,6-chloro-(9CI) is used as a precursor in the synthesis of potential anti-inflammatory and anti-cancer agents. Its biological and pharmacological properties are under investigation for their ability to modulate inflammatory responses and inhibit cancer cell growth, offering new avenues for therapeutic intervention in these areas.
Used in Research and Development:
3-Pyridinethiol,6-chloro-(9CI) is also utilized in research and development settings to explore its potential applications in various industries. Its unique chemical properties and reactivity make it a subject of interest for scientists working on new materials, chemical processes, and innovative solutions across different fields.
Check Digit Verification of cas no
The CAS Registry Mumber 558466-12-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,5,8,4,6 and 6 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 558466-12:
(8*5)+(7*5)+(6*8)+(5*4)+(4*6)+(3*6)+(2*1)+(1*2)=189
189 % 10 = 9
So 558466-12-9 is a valid CAS Registry Number.
InChI:InChI=1/C5H4ClNS/c6-5-2-1-4(8)3-7-5/h1-3,8H
558466-12-9Relevant articles and documents
PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND USE
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Paragraph 0509; 0511-0512, (2021/09/26)
The present invention provides, in part, novel small molecule inhibitors of PHD, having a structure according to Formula (A), and sub-formulas thereof: or a pharmaceutically acceptable salt thereof. The compounds provided herein can be useful for treatment of diseases including heart ( e.g. ischemic heart disease, congestive heart failure, and valvular heart disease), lung (e.g., acute lung injury, pulmonary hypertension, pulmonary fibrosis, and chronic obstructive pulmonary disease), liver (e.g. acute liver failure and liver fibrosis and cirrhosis), and kidney (e.g. acute kidney injury and chronic kidney disease) disease.
HETEROCYCLIC METHYL SULFONE DERIVATIVE
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Page/Page column 82-83; 95-96, (2010/11/08)
Provided is a compound capable of inhibiting production or secretion of β amyloid protein. A compound represented by the following formula (1): (wherein, R1 represents a heterocyclic group which may have a substituent, R2 represents a cyclic hydrocarbon group which may have a substituent or a heterocyclic group which may have a substituent, R3 represents a cyclic hydrocarbon group which may have a substituent or a heterocyclic group which may have a substituent, R4 represents a hydrogen atom or a C1-6 alkyl group, and X represents -S-,-SO- or -SO2-) an N-oxide or S-oxide thereof; a salt thereof; or a solvate thereof; and a medicament containing any of them.
BETA-AMYLOID PROTEIN PRODUCTION/SECRETION INHIBITORS
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Page 131, (2010/02/08)
Provided are novel compounds having an inhibitory activity against production or secretion of β-amyloid protein. They embrace compounds represented by the following formula (1): and capable of being replaced with a variety of substituents; and salts thereof, and solvates of any one of them.
