558473-98-6Relevant articles and documents
Coumarin-based fluorogenic agents and uses thereof for specific protein labelling
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Page/Page column 44, (2017/08/08)
There are provided fluorescent labelling agents comprising a dimaleimide core connected to a fluorophore, processes for preparation thereof, and uses thereof for labelling and/or detection of specific protein targets. Fluorescent labelling agents comprising a compound having the structure of Formula I, and salts thereof, are described.
Ring Substituent Effects on the Thiol Addition and Hydrolysis Reactions of N-Arylmaleimides
Chen, Yingche,Tsao, Kelvin,De Francesco, élise,Keillor, Jeffrey W.
, p. 12182 - 12192 (2016/01/09)
Maleimide groups are used extensively in bioconjugation reactions, but limited kinetic information is available regarding their thiol addition and hydrolysis reactions. We prepared a series of fluorogenic coumarin maleimide derivatives that differ by the
Facile routes to alkoxymaleimides/maleic anhydrides
Sahoo, Manoj Kumar,Mhaske, Santosh B.,Argade, Narshinha P.
, p. 346 - 349 (2007/10/03)
New routes to alkoxymaleic anhydrides 1a/b have been described in good yields via base-induced chemoselective vinylic substitution of bromo atom in bromomaleimide 4 with alkanols, and base-induced oxa-Micahel addition of alkanols to dialkyl acetylene-dicarboxylates 8a/b as key steps. An unusual acyl exchange in the conversion of 6a/b to 1a/b under very simple and mild reaction conditions is noteworthy.
