The synthesis of 2-alkyl-4-pyrones from meldrum's acid
-
Crimmins, Michael T.,Washburn, David G.,Zawacki, Frank J.,Pacholec, Michelle,Wolff, Steven
p. 114 - 114
(2017/09/25)
A convenient synthesis of unsymmetrical, substituted γ-pyrones from Meldrum's acid
A unique approach to the synthesis of mono and disubstituted γ-pyrones from acylated Meldrum's acid and vinyl ethers has been developed. The convenient one pot synthesis of these versatile polyketide equivalents is accomplished without strong base or low temperature.