561052-52-6

Basic information

• Product Name: 1-[AMINO-(3-NITRO-PHENYL)-METHYL]-NAPHTHALEN-2-OL
• Synonyms: 1-[AMINO-(3-NITRO-PHENYL)-METHYL]-NAPHTHALEN-2-OL
• CAS NO: 561052-52-6
• Molecular Formula: C₁₇H₁₄N₂O₃
• Molecular Weight: 294.3
• Mol File: 561052-52-6.mol

Chemical Properties

• Boiling Point: 513.2°C at 760 mmHg
• Flash Point: 264.2°C
• Appearance: /
• Density: 1.352g/cm³
• Vapor Pressure: 3.73E-11mmHg at 25°C
• Refractive Index: 1.713
• CAS DataBase Reference: 1-[AMINO-(3-NITRO-PHENYL)-METHYL]-NAPHTHALEN-2-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[AMINO-(3-NITRO-PHENYL)-METHYL]-NAPHTHALEN-2-OL(561052-52-6)
• EPA Substance Registry System: 1-[AMINO-(3-NITRO-PHENYL)-METHYL]-NAPHTHALEN-2-OL(561052-52-6)

Safety Data

• Hazardous Substances Data: 561052-52-6(Hazardous Substances Data)

Usage

Chemical structure

The chemical 1-[amino-(3-nitro-phenyl)-methyl]-naphthalen-2-ol is a compound with a naphthalene backbone attached to a 1-amino-3-nitrophenylmethyl group.

Naphthalene backbone

The naphthalene backbone is a fused ring system consisting of two benzene rings.

1-amino-3-nitrophenylmethyl group

This group is attached to the naphthalene backbone and contains an amine group attached to a 3-nitrophenylmethyl group.

Naphthalene-2-ol moiety

The naphthalene-2-ol moiety consists of a naphthalene ring with a hydroxyl group attached to the 2-position.

Amino group

The amino group (-NH2) is a functional group that contains a nitrogen atom bonded to two hydrogen atoms.

3-nitrophenylmethyl group

This group contains a nitro group (-NO2) attached to a phenyl ring, which is in turn bonded to a methyl group (-CH3).

Hydroxyl group

The hydroxyl group (-OH) is a functional group that contains an oxygen atom bonded to a hydrogen atom.

Potential applications

This chemical may have various applications in research and industrial processes.

Safety precautions

Proper safety measures, such as wearing protective gear and following safety protocols, should be taken when handling and using this chemical.

InChI:InChI=1/C17H14N2O3/c18-17(12-5-3-6-13(10-12)19(21)22)16-14-7-2-1-4-11(14)8-9-15(16)20/h1-10,17,20H,18H2

Upstream product

• 135-19-3 β-naphthol 
• 99-61-6 3-nitro-benzaldehyde 

Relevant articles and documents

High-performance liquid chromatographic enantioseparation of Betti base analogs on a newly developed isopropyl carbamate-cyclofructan6-based chiral stationary phase

The direct separation of the enantiomers of 1-(α-aminoarylmethyl)-2- naphthol, 1-(α-aminoalkyl)-2-naphthol, 2-(α-aminoarylmethyl)-1- naphthol analogs, and 2-(1-amino-2-methylpropyl)-1-naphthol) was performed on a newly developed chiral stationary phase containing isopropyl carbamate-cyclofructan6 as chiral selector, with n-heptane/alcohol/ trifluoroacetic acid as mobile phase. The effects of the mobile-phase composition, the nature and concentration of the alcoholic and acidic modifiers, and the structures of the analytes on the retention and resolution were investigated. In some cases, separations were carried out at constant mobile-phase compositions in the temperature range 5-40°C. Thermodynamic parameters and Tiso values were calculated from plots of ln k′ or ln α versus 1/T. -Δ(ΔH°) ranged from 2.8 to 3.2 kJ mol-1, -Δ(ΔS°) from 7.7 to 10.1 J mol-1 K-1, and -Δ(ΔG°) from 0.2 to 0.5 kJ mol-1. It was found that the enantioseparations were enthalpy driven. The sequence of elution of the stereoisomers determined in some cases was (R) (S).

Substituent effects in the ring-chain tautomerism of 1,3-diaryl-2,3-dihydro-1H-naphth[1,2-e][1,3]oxazines

Condensation of Betti base analogue amino naphthols with substituted benzaldehydes led to 1,3-diaryl-2,3-dihydro-1H-naphth[1,2-e][1,3]oxazines (3-9) which proved to be three-component (r1-o-r2) tautomeric mixtures in CDCl3