- Syntheses, Structures and Sorption Properties of Three Isoreticular Trinuclear Indium-Based Amide-Functionalized Metal–Organic Frameworks
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Amide-functionalized metal–organic frameworks (AFMOFs) as a subclass of MOF materials have received great interest recently because of their intriguing structures and diverse potential applications. In this work, solvothermal reactions between indium nitrate and two mixed-linkers afforded two new isoreticular 8-connected trinuclear indium-based AFMOFs of [(In3O)(OH)(L2)2(IN)2]?(solv)x (2-In) and [(In3O)(OH)(L2)2(AIN)2]?(solv)x (NH2-2-In) (H2L2=4,4′-(carbonylimino)dibenzoic acid and HIN=isonicotinic acid or HAIN=3-aminoisonicotinic acid), respectively. Moreover, by means of reticular chemistry, an extended network of [(In3O)(OH)(L3)2(PB)2]?(solv)x (3-In) (H2L3=4,4′-(terephthaloylbis(azanediyl))dibenzoic acid, HPB=4-(4-pyridyl)benzoic acid) was also successfully realized after prolongation of the former dicarboxylate linker and HIN, resulting in a truly 8-connected isoreticular AFMOF platform. These frameworks were structurally determined by single-crystal X-ray diffraction (SCXRD). Sorption studies further demonstrate that 2-In and NH2-2-In exhibit not only high surface areas and pore volumes but also relatively high carbon capture capabilities (the CO2 uptakes reach 60.0 and 75.5 cm3 g?1 at 298 K and 760 torr, respectively) due to the presences of amide and/or amine functional groups. The selectivity of CO2/N2 and CO2/CH4 calculated by IAST are 10.18 and 12.43, 4.20 and 4.23 for 2-In and NH2-2-In, respectively, which were additionally evaluated by mixed-gases dynamic breakthrough experiments. In addition, high-pressure gas sorption measurements show that both materials could take up moderate amounts of natural gas.
- Zhang, Zong-Hui,Wang, Qian,Xue, Dong-Xu,Bai, Junfeng
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p. 3603 - 3610
(2019/06/24)
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- SULFURIC ACID ESTERS OF SUGAR ALCOHOLS
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The present invention is concerned with novel sulfuric acid esters of sugar alcohols and sugar alcohol-like compounds of the formula STR1 Also described are methods for the treatment and/or prophylaxis of arteriosclerotic changes in the vascular wall as well as a process for the manufacture of the compounds of formula I and their salts.
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- Mesogenic glycidyl esters
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Glycidyl esters are disclosed which contain mesogenic moieties which result in improved properties when cured.
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- Antiallergic and cytoprotective activity of new N-phenylbenzamido acid derivatives
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A series of new N-phenylbenzamido acid derivatives was synthesized and evaluated for their ability to inhibit the IgE-mediated passive cutaneous anaphylaxis in the rat (PCA), as well as for their capacity to inhibit gastric mucosal damage induced by the oral administration of absolute alcohol in the rat. Some of these new derivatives exhibit potent antiallergic and cytoprotective activity, 20-80 times higher than that of the reference, disodium cromoglycate (DSCG). Structure-activity relationships are discussed. The antiallergic activity of one of the more potent compounds of this series, i.e. 4-(1H-tetrazol-5-yl)-N-[4-(1H-tetrazol-5-yl)phenyl]benzamide (compound 44, CR 2039) was further evaluated in vivo. This compound antagonizes the bronchoconstriction induced by aerosolized ovalbumin in both anesthetized and conscious IgE sensitized guinea pigs with ID50 of 3.7 mg/animal (tracheal insufflation) and 20 mg/kg (im). Further cytoprotective effects were evaluated in gastric ulcer models induced by the acute oral administration of hypertonic sodium chloride solution or by acetic acid and by the subchronic administration of glucose in fasted animals. In the models used experimentally CR 2039 is effective, whereas DSCG seems to be devoid of any protective activity. Such a potent antiallergic and mucosal protectant could provide a new potential agent in the therapy of atopic allergic diseases.
- Makovec,Peris,Revel,Giovanetti,Redaelli,Rovati
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p. 3633 - 3640
(2007/10/02)
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