Ketoamide-based inhibitors of cysteine protease, cathepsin K: P3 modifications
Osteoporosis is a disease characterized by skeletal fragility. Cathepsin K, a lysosomal cysteine protease, has been implicated in the osteoclast mediated bone resorption. Inhibitors of this protease could potentially treat this skeletal disease. The prese
Tavares, Francis X.,Deaton, David N.,Miller, Larry R.,Wright, Lois L.
p. 5057 - 5068
(2007/10/03)
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