Evaluation of Phosphinic Acid Derivatives as Reagents For Amine Protection in Peptide Synthesis
The results of a kinetic study of the acid-catalysed methanolysis of a series of N-(2-phenyl-ethyl)phosphinamides incorporating selected substituents on phosphorus have been evaluated in order to define the optimum reagent and conditions for amine protection of α-amino acids during peptide synthesis.
Ramage, Robert,Atrash, Butrus,Hopton, David,Parrot, Maxwell J.
p. 1217 - 1226
(2007/10/02)
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