- Biotransformation of androst-4-ene-3,17-dione by some fungi
-
The incubations of androst-4-ene-3,17-dione with Aspergillus candidus MRC 200634, Aspergillus tamarii MRC 72400, Aspergillus wentii MRC 200316 and Mucor hiemalis MRC 70325 for 5 days are reported. A. candidus MRC 200634 mainly hydroxylated androst-4-ene-3,17-dione at C-11α, C-15α and C-15β whilst A. wentii MRC 200316 hydroxylated it mainly at C-6β. A. tamarii MRC 72400 showed predominately a Baeyer–Villiger monooxygenase activity. M. hiemalis MRC 70325 hydroxylated the substrate at C-14α and reduced most of it at C-17.
- Yildirim, Kudret,Kuru, Ali,Keskin, Ece,Salihoglu, Aylin,Bukum, Neslihan
-
p. 594 - 597
(2017/11/14)
-
- A GENERAL METHOD FOR THE SELECTIVE REDUCTION OF KETONES IN THE PRESENCE OF ENONES.
-
Ketones can be reduced in the presence of conjugated enones by sodium borohydride in 50percent methanol in dichloromethane at -78 deg C.The selectivity is generally excellent.In favorable cases the reaction can be carried out at room temperature in dichloromethane with acetic acid as catalyst.
- Ward, Dale E.,Rhee, Chung K.,Zoghaib, Wajdi M.
-
p. 517 - 520
(2007/10/02)
-
