- A new method for bromination of carbazoles, β-carbolines and iminodibenzyls by use of N-bromosuccinimide and silica gel
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Carbazole, N-ethylcarbazole, iminodibenzyl (10,11-dihydro-5H-dibenz[b,f]azepine), N-ethyliminodibenzyl and imipramine are readily mono-, di- or polybrominated in high yields at ambient temperature in dichloromethane by use of the appropriate quantity of N-bromosuccinimide in the presence of silica gel. By contrast, the brominations of the β-carbolines, harmane and norharman, are less selective and give mixtures of products, some of which have unusual substitution patterns.
- Smith, Keith,Martin James,Mistry, Anil G.,Bye, Martin R.,John Faulkner
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p. 7479 - 7488
(2007/10/02)
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