Kinetic Optimization of Lysine-Targeting Covalent Inhibitors of HSP72
The covalent inhibition mechanism of action, which overcomes competition with high-affinity, high-abundance substrates of challenging protein targets, can deliver effective chemical probes and drugs. The success of this strategy has centered on exposed cy
Pettinger, Jonathan,Carter, Michael,Jones, Keith,Cheeseman, Matthew D.
p. 11383 - 11398
(2019/12/30)
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