- A simple route to 6- and 7-fluoro-substituted naphthalene-1-carboxylic acids
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A simple one-pot method for the synthesis of 6-fluoro- and 6,7-difluoro-1-naphthoic acid is described. 6-Fluoro-1-naphthoic acid can be converted into 7-fluoro-1-naphthoic acid in three straightforward steps.
- Krülle, Thomas M.,Barba, Oscar,Davis, Susan H.,Dawson, Graham,Procter, Martin J.,Staroske, Thomas,Thomas, Gerard H.
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p. 1537 - 1540
(2008/02/02)
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- DIHYDROIMIDAZOTHIAZOLE DERIVATIVES
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Compounds of formula (I): or pharmaceutically acceptable salts thereof, exhibit 5-HT1A agonism in addition to noradrenaline reuptake inhibition and optionally also 5-HT reuptake inhibition are useful for the treatment of obesity.
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Page/Page column 64
(2008/06/13)
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- Arylpiperazinyl-alkylene-phenyl-heterocyclic compounds
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Arylpiperazinyl-alkylenephenyl-p-heterocyclic compounds, and the pharmaceutically acceptable acid addition salts thereof are neuroleptic agents. They are useful in the treatment of psychotic disorders.
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- Arylpiperazinyl-alkylene-phenyl-heterocyclic compounds
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An arylpiperazinyl-alkylenephenyl-p-heterocyclic compound, useful in the treatment of psychotic disorders, of the formula- or a pharmaceutically-acceptable acid-addition salt thereof,wherein:-, Ar is phenyl, 3-trifluoromethylphenyl, 3-cyanopyridyl, naphth
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