Inhibition of protein kinase C by dequalinium analogues: Structure-activity studies on head group variations
New dequalinium analogues and related heteroaromatic systems were synthesized and evaluated for inhibition of protein kinase Cα. In vitro assays with recombinant human PKCα showed that the number of the aromatic ring head groups as well as their electron-
Abeywickrama, Chandima,Rotenberg, Susan A.,Baker, Arthur David