- 167. Ueber die Strukturaufklaerung von (Hydroxy-oxo-cyclopentenyl)alkansaeuren, den Aldolkondensationsprodukten von Dioxoencarbonsaeuren aus Rinderleber
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During homogenization of cattle liver the highly instable dioxoene acids 13a, 13b, and 13c are formed.These acids cyclize in alkaline solution to yield pairs of stable (hydroxy-oxo-cyclopentenyl)alkanoic acids, which were isolated as methyl esters 4a/5a, 4b/5b, and 4c/5c.The structures of these compounds were deduced from an enriched 3-mg mixture sample by microchemical reactions combined with a GC/MS analysis of the reaction products.Compound 13a was obtained as methyl ester by oxidation of the methyl ester of the corresponding F-acid with NaOCl.It was not possible to isolate 13a in pure form due to its high sensitivity.Instead of the methyl ester of 13a, 4a and 5a were isolated, of which the structures were established.
- Schoedel, Rolf,Spiteller, Gerhard
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p. 1624 - 1634
(2007/10/02)
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