58207-19-5

Basic information

• Product Name: CLINDAMYCIN HYDROCHLORIDE
• Synonyms: U-21251F;(7S)-7-CHLORO-7-DEOXYLINCOMYCIN HYDROCHLORIDE;7(S)-CHLORO-7-DEOXYLINCOMYCIN;7(S)-CHLORO-7-DEOXYLINCOMYCIN HCL;7[S]-CHLORO-7-DEOXYLINCOMYCIN HYDROCHLORIDE;(2S-TRANS)-METHYL 7-CHLORO-6,7,8-TRIDEOXY-6[[(1-METHYL-4-PROPYL-2-PYRROLIDINYL)CARBONYL]AMINO]-1-THIO-L-THREO-ALPHA-D-GALACTO-OCTOPYRANOSIDE;CLEOCIN;CLEOCIN HYDROCHLORIDE
• CAS NO: 58207-19-5
• Molecular Formula: C₁₂H₂₀O₂
• Molecular Weight: 461.44
• EINECS: 244-398-6
• Product Categories: Active Pharmaceutical Ingredients;Antibiotics for Research and Experimental Use;Biochemistry;Others (Antibiotics for Research and Experimental Use);Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 58207-19-5.mol

Chemical Properties

• Melting Point: 143 °C
• Boiling Point: 647oC at 760 mmHg
• Flash Point: 345.1oC
• Appearance: /
• Refractive Index: 143 ° (C=2, H2O)
• Storage Temp.: 2-8°C
• Water Solubility: Soluble in water
• Merck: 14,2356
• CAS DataBase Reference: CLINDAMYCIN HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: CLINDAMYCIN HYDROCHLORIDE(58207-19-5)
• EPA Substance Registry System: CLINDAMYCIN HYDROCHLORIDE(58207-19-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39-24/25
• WGK Germany: 3
• RTECS: GF2275000
• HazardClass: 3
• Hazardous Substances Data: 58207-19-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Clindamycin Hydrochloride is used as an antibiotic for the treatment of various bacterial infections caused by susceptible organisms. It is particularly effective against gram-positive bacteria and certain anaerobic bacteria. The antibiotic is prescribed for conditions such as skin and soft tissue infections, respiratory tract infections, bone and joint infections, and intra-abdominal infections.
Used in Hospital Settings:
Clindamycin Hydrochloride is used as an antibacterial agent in hospital settings to treat serious infections that require intravenous administration. It is often used in combination with other antibiotics to provide broad-spectrum coverage against a range of bacteria.
Used in Dental Practice:
In dental practice, Clindamycin Hydrochloride is used as an antibiotic to treat infections associated with dental procedures, such as tooth extractions, root canals, and periodontal treatments. It helps to prevent and control bacterial infections that may arise from these procedures.
Used in Veterinary Medicine:
Clindamycin Hydrochloride is also used in veterinary medicine as an antibiotic to treat bacterial infections in animals, such as skin infections, respiratory infections, and wound infections.

InChI:InChI=1/C18H33ClN2O5S.ClH/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4;/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25);1H/t9?,10-,11+,12?,13+,14-,15?,16?,18?;/m1./s1

Upstream product

• 108-24-7 acetic anhydride 
• 10482-56-1 (-)-(S)-α-terpineol 

Relevant articles and documents

Heteropoly acid catalysts for the synthesis of fragrance compounds from bio-renewables: Acetylation of nopol and terpenic alcohols

The cesium salt of tungstophosphoric heteropoly acid, Cs2.5H0.5PW12O40, is an active and environmentally friendly heterogeneous catalyst for the liquid-phase acetylation of nopol and several biomass-derived terpenic alcohols (i.e., α-terpineol, nerol, geraniol, linalool, menthol, isoborneol, perillyl alcohol, carveol, isopulegol, carvacrol and nerolidol) with acetic anhydride. The resulting flavor and fragrance acetic esters, which are widely used in perfumery, household and food products, are obtained in good to excellent yields. The reactions occur at room temperature with low catalyst loadings without substantial catalyst leaching and can be performed with stoichiometric amounts of an acetylating agent in solvent free systems.