An efficient synthesis of uracil derivatives from 2-alkyl-Δ2-oxazolines and nitriles
An efficient and convenient synthesis of new fluorinated and non-fluorinated uracils is described herein. The condensation of nitriles with enolates generated from 2-alkyl-Δ2-oxazolines (I) affords fluorinated β-enamino acid derivatives, which
Fustero, Santos,Sanz-Cervera, Juan F.,Mérida, Salvador,Román, Raquel,Villanova, Salvador,Ramírez de Arellano, Carmen
experimental part
p. 836 - 847
(2009/04/11)
An efficient synthesis of new fluorinated uracil derivatives.
A series of potentially biologically active fluorinated uracil derivatives has been prepared in three steps from oxazolines and fluorinated nitriles with good chemical yields.
Fustero, Santos,Salavert, Esther,Sanz-Cervera, Juan F,Piera, Julio,Asensio, Amparo
p. 844 - 845
(2007/10/03)
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