- Alternative and straightforward synthesis of dopaminergic 5-methoxy-1,2,3,4-tetrahydronaphthalen-2-amine
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5-Methoxy-1,2,3,4-tetrahydronaphthalen-2-amine was synthesized from 2-naphthoic acid in six steps with an overall yield of 27%. Following the reaction sequence, bromination, esterification, substitution with NaOMe in the presence of CuI, the Birch reducti
- Oeztaskin, Necla,Goeksu, Sueleyman,Hasan Secen
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p. 2017 - 2024
(2011/06/24)
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- α-Adrenergic Agents. 2. Synthesis and α1-Agonist Activity of 2-Aminotetralins
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Substituted 2-aminotetralins are potent, selective, direct-acting agonists as postjunctional α1 receptors.Within this series, substituent alterations on the ring, as well as on the nitrogen, change the potency of compounds by over three orders
- DeMarinis, R. M.,Shah, D. H.,Hall, R. F.,Hieble, J. P.,Pendleton, R. G.
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p. 136 - 141
(2007/10/02)
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