cas 58534-94-4, 3-BROMO-2-FLUORONITROBENZENE | Articles data ｜lookchem

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58534-94-4

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3-bromo-2-fluoronitrobenzene preparation method
The invention discloses a 3-bromo-2-fluoronitrobenzene preparation method. The method includes steps: (1) under the alkali action, subjecting bromoaniline and acetyl chloride to acetylation to obtainN-(2-bromophenyl)acetamide; (2) subjecting N-(2-bromophe
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Paragraph 0071-0088

(2019/10/23)

Synthesis and structure-activity studies of novel benzocycloheptanone oxazolidinone antibacterial agents
We describe a novel class of benzocycloheptanone derived oxazolidinone antibacterial agents. The synthesis and antibacterial activities with structure variation is discussed.
Vara Prasad,Boyer, Frederick E.,Chupak, Lou,Dermyer, Michael,Ding, Qizhu,Gavardinas,Hagen, Susan E.,Huband, Michael D.,Jiao, Wenhua,Kaneko, Takushi,Maiti, Samarendra N.,Melnick, Michael,Romero, Karina,Patterson,Wu, Xiujuan
p. 5392 - 5397
(2007/10/03)

ANTIBACTERIAL AGENTS
Compounds of formula I and methods for their preparation are disclosed. Further disclosed are methods of making biologically active compounds of formula I as well as pharmaceutically acceptable compositions comprising compounds of formula I. Compounds of formula I as disclosed herein can be used in a variety of applications including use as antibacterial agents.
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Page 127

(2010/02/08)

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Chemical Properties

Melting Point: 29-31 °C
Boiling Point: 259.1 °C at 760 mmHg
Flash Point:110.5 °C
Density: 1.808 g/cm³
Storage Temp.:Sealed in dry,Room Temperature
Vapor Pressure: 0.0214mmHg at 25°C
Refractive Index: 1.579
PSA: 45.82000
LogP: 3.01960

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